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Protein painting reveals solvent-excluded drug targets hidden within native protein–protein interfaces
Identifying the contact regions between a protein and its binding partners is essential for creating therapies that block the interaction. Unfortunately, such contact regions are extremely difficult to characterize because they are hidden inside the binding interface. Here we introduce protein paint...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109009/ https://www.ncbi.nlm.nih.gov/pubmed/25048602 http://dx.doi.org/10.1038/ncomms5413 |