Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry

This study involving 1033 patients with RA confirms the effectiveness of etanercept, adalimumab, and infliximab in reducing RA-related disability even in patients with a history of highly active and longstanding RA. Moreover, we found that the improvement in disability was biphasic, with a marked im...

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Detalles Bibliográficos
Autores principales: Filippini, Matteo, Bazzani, Chiara, Atzeni, Fabiola, Sarzi Puttini, Piercarlo, Marchesoni, Antonio, Favalli, Ennio Giulio, Caporali, Roberto, Cavagna, Lorenzo, Gorla, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109221/
https://www.ncbi.nlm.nih.gov/pubmed/25110678
http://dx.doi.org/10.1155/2014/416892
Descripción
Sumario:This study involving 1033 patients with RA confirms the effectiveness of etanercept, adalimumab, and infliximab in reducing RA-related disability even in patients with a history of highly active and longstanding RA. Moreover, we found that the improvement in disability was biphasic, with a marked improvement during the first year of anti-TNF therapy, followed by slower but significant recovery over the subsequent four years.

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