Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry

This study involving 1033 patients with RA confirms the effectiveness of etanercept, adalimumab, and infliximab in reducing RA-related disability even in patients with a history of highly active and longstanding RA. Moreover, we found that the improvement in disability was biphasic, with a marked im...

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Autores principales: Filippini, Matteo, Bazzani, Chiara, Atzeni, Fabiola, Sarzi Puttini, Piercarlo, Marchesoni, Antonio, Favalli, Ennio Giulio, Caporali, Roberto, Cavagna, Lorenzo, Gorla, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109221/
https://www.ncbi.nlm.nih.gov/pubmed/25110678
http://dx.doi.org/10.1155/2014/416892
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author Filippini, Matteo
Bazzani, Chiara
Atzeni, Fabiola
Sarzi Puttini, Piercarlo
Marchesoni, Antonio
Favalli, Ennio Giulio
Caporali, Roberto
Cavagna, Lorenzo
Gorla, Roberto
author_facet Filippini, Matteo
Bazzani, Chiara
Atzeni, Fabiola
Sarzi Puttini, Piercarlo
Marchesoni, Antonio
Favalli, Ennio Giulio
Caporali, Roberto
Cavagna, Lorenzo
Gorla, Roberto
author_sort Filippini, Matteo
collection PubMed
description This study involving 1033 patients with RA confirms the effectiveness of etanercept, adalimumab, and infliximab in reducing RA-related disability even in patients with a history of highly active and longstanding RA. Moreover, we found that the improvement in disability was biphasic, with a marked improvement during the first year of anti-TNF therapy, followed by slower but significant recovery over the subsequent four years.
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spelling pubmed-41092212014-08-10 Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry Filippini, Matteo Bazzani, Chiara Atzeni, Fabiola Sarzi Puttini, Piercarlo Marchesoni, Antonio Favalli, Ennio Giulio Caporali, Roberto Cavagna, Lorenzo Gorla, Roberto Biomed Res Int Research Article This study involving 1033 patients with RA confirms the effectiveness of etanercept, adalimumab, and infliximab in reducing RA-related disability even in patients with a history of highly active and longstanding RA. Moreover, we found that the improvement in disability was biphasic, with a marked improvement during the first year of anti-TNF therapy, followed by slower but significant recovery over the subsequent four years. Hindawi Publishing Corporation 2014 2014-07-06 /pmc/articles/PMC4109221/ /pubmed/25110678 http://dx.doi.org/10.1155/2014/416892 Text en Copyright © 2014 Matteo Filippini et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Filippini, Matteo
Bazzani, Chiara
Atzeni, Fabiola
Sarzi Puttini, Piercarlo
Marchesoni, Antonio
Favalli, Ennio Giulio
Caporali, Roberto
Cavagna, Lorenzo
Gorla, Roberto
Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry
title Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry
title_full Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry
title_fullStr Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry
title_full_unstemmed Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry
title_short Effects of Anti-TNF Alpha Drugs on Disability in Patients with Rheumatoid Arthritis: Long-Term Real-Life Data from the Lorhen Registry
title_sort effects of anti-tnf alpha drugs on disability in patients with rheumatoid arthritis: long-term real-life data from the lorhen registry
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109221/
https://www.ncbi.nlm.nih.gov/pubmed/25110678
http://dx.doi.org/10.1155/2014/416892
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