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GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation

GSK-3 is an essential mediator of several signaling pathways that regulate cortical development. We therefore created conditional mouse mutants lacking both GSK-3α and GSK-3β in newly born cortical excitatory neurons. Gsk3-deleted neurons expressing upper layer markers exhibited striking migration f...

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Detalles Bibliográficos
Autores principales:	Morgan-Smith, Meghan, Wu, Yaohong, Zhu, Xiaoqin, Pringle, Julia, Snider, William D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109311/ https://www.ncbi.nlm.nih.gov/pubmed/25073924 http://dx.doi.org/10.7554/eLife.02663

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