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Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants

Protein folding homeostasis in the endoplasmic reticulum (ER) requires efficient protein thiol oxidation, but also relies on a parallel reductive process to edit disulfides during the maturation or degradation of secreted proteins. To critically examine the widely held assumption that reduced ER glu...

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Detalles Bibliográficos
Autores principales:	Tsunoda, Satoshi, Avezov, Edward, Zyryanova, Alisa, Konno, Tasuku, Mendes-Silva, Leonardo, Pinho Melo, Eduardo, Harding, Heather P, Ron, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109312/ https://www.ncbi.nlm.nih.gov/pubmed/25073928 http://dx.doi.org/10.7554/eLife.03421

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