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Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish
Most neuroactive drugs were discovered through unexpected behavioral observations. Systematic behavioral screening is inefficient in most model organisms. But, automated technologies are enabling a new phase of discovery-based research in central nervous system (CNS) pharmacology. Researchers are us...
Autores principales: | Bruni, Giancarlo, Lakhani, Parth, Kokel, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109429/ https://www.ncbi.nlm.nih.gov/pubmed/25104936 http://dx.doi.org/10.3389/fphar.2014.00153 |
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