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Composition and applications of focus libraries to phenotypic assays
The wealth of bioactivity information now available on low-molecular weight compounds has enabled a paradigm shift in chemical biology and early phase drug discovery efforts. Traditionally chemical libraries have been most commonly employed in screening approaches where a bioassay is used to charact...
Autores principales: | Wassermann, Anne Mai, Camargo, Luiz M., Auld, Douglas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109565/ https://www.ncbi.nlm.nih.gov/pubmed/25104937 http://dx.doi.org/10.3389/fphar.2014.00164 |
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