Cargando…
An Intronic microRNA Links Rb/E2F and EGFR Signaling
The importance of microRNAs in the regulation of various aspects of biology and disease is well recognized. However, what remains largely unappreciated is that a significant number of miRNAs are embedded within and are often co-expressed with protein-coding host genes. Such a configuration raises th...
Autores principales: | Truscott, Mary, Islam, Abul B. M. M. K., Lightfoot, James, López-Bigas, Núria, Frolov, Maxim V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109884/ https://www.ncbi.nlm.nih.gov/pubmed/25058496 http://dx.doi.org/10.1371/journal.pgen.1004493 |
Ejemplares similares
-
Novel regulation and functional interaction of polycistronic miRNAs
por: Truscott, Mary, et al.
Publicado: (2016) -
Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells
por: Váraljai, Renáta, et al.
Publicado: (2015) -
Differentiation-associated microRNAs antagonize the Rb–E2F pathway to restrict proliferation
por: Marzi, Matteo J., et al.
Publicado: (2012) -
Intronic MicroRNA (miRNA)
por: Lin, Shi-Lung, et al.
Publicado: (2006) -
Expression patterns of intronic microRNAs in Caenorhabditis elegans
por: Isik, Meltem, et al.
Publicado: (2010)