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Functional EF-Hands in Neuronal Calcium Sensor GCAP2 Determine Its Phosphorylation State and Subcellular Distribution In Vivo, and Are Essential for Photoreceptor Cell Integrity

The neuronal calcium sensor proteins GCAPs (guanylate cyclase activating proteins) switch between Ca(2+)-free and Ca(2+)-bound conformational states and confer calcium sensitivity to guanylate cyclase at retinal photoreceptor cells. They play a fundamental role in light adaptation by coupling the ra...

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Detalles Bibliográficos
Autores principales:	Hoyo, Natalia López-del, López-Begines, Santiago, Rosa, Jose Luis, Chen, Jeannie, Méndez, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109901/ https://www.ncbi.nlm.nih.gov/pubmed/25058152 http://dx.doi.org/10.1371/journal.pgen.1004480

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