A Crucial Role for CDC42 in Senescence-Associated Inflammation and Atherosclerosis

Risk factors for atherosclerosis accelerate the senescence of vascular endothelial cells and promote atherogenesis by inducing vascular inflammation. A hallmark of endothelial senescence is the persistent up-regulation of pro-inflammatory genes. We identified CDC42 signaling as a mediator of chronic...

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Detalles Bibliográficos
Autores principales: Ito, Takashi K., Yokoyama, Masataka, Yoshida, Yohko, Nojima, Aika, Kassai, Hidetoshi, Oishi, Kengo, Okada, Sho, Kinoshita, Daisuke, Kobayashi, Yoshio, Fruttiger, Marcus, Aiba, Atsu, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109913/
https://www.ncbi.nlm.nih.gov/pubmed/25057989
http://dx.doi.org/10.1371/journal.pone.0102186

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