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Immunization of Mice with Lentiviral Vectors Targeted to MHC Class II+ Cells Is Due to Preferential Transduction of Dendritic Cells In Vivo
Gene transfer vectors such as lentiviral vectors offer versatile possibilities to express transgenic antigens for vaccination purposes. However, viral vaccines leading to broad transduction and transgene expression in vivo, are undesirable. Therefore, strategies capable of directing gene transfer on...
Autores principales: | Ciré, Séverine, Da Rocha, Sylvie, Yao, Roseline, Fisson, Sylvain, Buchholz, Christian J., Collins, Mary K., Galy, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109917/ https://www.ncbi.nlm.nih.gov/pubmed/25058148 http://dx.doi.org/10.1371/journal.pone.0101644 |
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