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Design, Synthesis and Pharmacological Evaluation of Novel Vanadium-Containing Complexes as Antidiabetic Agents
Based on the data about structure and antidiabetic activity of twenty seven vanadium and zinc coordination complexes collected from literature we developed QSAR models using the GUSAR program. These QSAR models were applied to 10 novel vanadium coordination complexes designed in silico in order to p...
Autores principales: | Fedorova, Elena V., Buryakina, Anna V., Zakharov, Alexey V., Filimonov, Dmitry A., Lagunin, Alexey A., Poroikov, Vladimir V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109918/ https://www.ncbi.nlm.nih.gov/pubmed/25057899 http://dx.doi.org/10.1371/journal.pone.0100386 |
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