B Cell Receptor Signaling-Based Index as a Biomarker for the Loss of Peripheral Immune Tolerance in Autoreactive B Cells in Rheumatoid Arthritis

This study examines the loss of peripherally induced B cell immune tolerance in Rheumatoid arthritis (RA) and establishes a novel signaling-based measure of activation in a subset of autoreactive B cells - the Induced tolerance status index (ITSI). Naturally occurring naïve autoreactive B cells can...

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Detalles Bibliográficos
Autores principales: Lyubchenko, Taras, Zerbe, Gary O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109936/
https://www.ncbi.nlm.nih.gov/pubmed/25057856
http://dx.doi.org/10.1371/journal.pone.0102128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109936/
https://www.ncbi.nlm.nih.gov/pubmed/25057856
http://dx.doi.org/10.1371/journal.pone.0102128

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