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Arginase Inhibition Ameliorates Hepatic Metabolic Abnormalities in Obese Mice
OBJECTIVES: We examined whether arginase inhibition influences hepatic metabolic pathways and whole body adiposity in diet-induced obesity. METHODS AND RESULTS: After obesity induction by a high fat diet (HFD), mice were fed either the HFD or the HFD with an arginase inhibitor, N(ω)-hydroxy-nor-L-ar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109998/ https://www.ncbi.nlm.nih.gov/pubmed/25057910 http://dx.doi.org/10.1371/journal.pone.0103048 |