Cargando…

Cellular Changes in Blood Indicate Severe Respiratory Disease during Influenza Infections in Mice

Influenza A infection is a serious threat to human and animal health. Many of the biological mechanisms of the host-pathogen-interactions are still not well understood and reliable biomarkers indicating the course of the disease are missing. The mouse is a valuable model system enabling us to study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dengler, Leonie, Kühn, Nora, Shin, Dai-Lun, Hatesuer, Bastian, Schughart, Klaus, Wilk, Esther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110021/ https://www.ncbi.nlm.nih.gov/pubmed/25058639 http://dx.doi.org/10.1371/journal.pone.0103149

Ejemplares similares

The Interferon-Induced Gene Ifi27l2a is Active in Lung Macrophages and Lymphocytes After Influenza A Infection but Deletion of Ifi27l2a in Mice Does Not Increase Susceptibility to Infection
por: Tantawy, Mohamed A., et al.
Publicado: (2014)

Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background
por: Shin, Dai-Lun, et al.
Publicado: (2015)

Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection
por: Dengler, Leonie, et al.
Publicado: (2012)

RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection
por: Wilk, Esther, et al.
Publicado: (2015)

Tmprss2 Is Essential for Influenza H1N1 Virus Pathogenesis in Mice
por: Hatesuer, Bastian, et al.
Publicado: (2013)

Segregation of a Spontaneous Klrd1 (CD94) Mutation in DBA/2 Mouse Substrains
por: Shin, Dai-Lun, et al.
Publicado: (2014)

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice
por: Leist, Sarah R., et al.
Publicado: (2016)

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
por: Kühn, Nora, et al.
Publicado: (2016)

Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains
por: Preusse, Matthias, et al.
Publicado: (2015)

Global Transcriptome Analysis in Influenza-Infected Mouse Lungs Reveals the Kinetics of Innate and Adaptive Host Immune Responses
por: Pommerenke, Claudia, et al.
Publicado: (2012)

Respiratory Mucosal Proteome Quantification in Human Influenza Infections
por: Marion, Tony, et al.
Publicado: (2016)

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice
por: Leist, Sarah R., et al.
Publicado: (2016)

Dynamic gene network reconstruction from gene expression data in mice after influenza A (H1N1) infection
por: Dimitrakopoulou, Konstantina, et al.
Publicado: (2011)

Highly dampened blood transcriptome response in HIV patients after respiratory infection
por: Sellers, Subhashini A., et al.
Publicado: (2021)

Author Correction: Highly dampened blood transcriptome response in HIV patients after respiratory infection
por: Sellers, Subhashini A., et al.
Publicado: (2021)

Genetically diverse CC-founder mouse strains replicate the human influenza gene expression signature
por: Elbahesh, Husni, et al.
Publicado: (2016)

Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice
por: Lambertz, Ruth L. O., et al.
Publicado: (2018)

Inhibition of lung serine proteases in mice: a potentially new approach to control influenza infection
por: Bahgat, Mahmoud M, et al.
Publicado: (2011)

Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection
por: Preusse, Matthias, et al.
Publicado: (2017)

Sustained viral load and late death in Rag2-/- mice after influenza A virus infection
por: Wu, Haiya, et al.
Publicado: (2010)

Toxocara canis- and Toxocara cati-Induced Neurotoxocarosis Is Associated with Comprehensive Brain Transcriptomic Alterations
por: Waindok, Patrick, et al.
Publicado: (2022)

Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection
por: Kim, So Yeon, et al.
Publicado: (2016)

Of mice and men: the host response to influenza virus infection
por: Kollmus, Heike, et al.
Publicado: (2018)

Equivalence of Self- and Staff-Collected Nasal Swabs for the Detection of Viral Respiratory Pathogens
por: Akmatov, Manas K., et al.
Publicado: (2012)

Influenza A and Respiratory Syncytial Virus Trigger a Cellular Response That Blocks Severe Acute Respiratory Syndrome Virus 2 Infection in the Respiratory Tract
por: Dee, Kieran, et al.
Publicado: (2022)

Long-Term Consequence of Non-neurotropic H3N2 Influenza A Virus Infection for the Progression of Alzheimer’s Disease Symptoms
por: Hosseini, Shirin, et al.
Publicado: (2021)

Infection- and procedure-dependent effects on pulmonary gene expression in the early phase of influenza A virus infection in mice
por: Preusse, Matthias, et al.
Publicado: (2013)

Impaired beta-oxidation increases vulnerability to influenza A infection
por: van Liempd, Sebastiaan, et al.
Publicado: (2021)

TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads
por: Low, Hui Zhi, et al.
Publicado: (2016)

Indicators of Hypoxia Tolerance as Determined by Cellular Elements of Rat Blood
por: Kondashevskaya, M. V., et al.
Publicado: (2021)

ICU respiratory admissions data for influenza severity surveillance?
por: van Asten, Liselotte, et al.
Publicado: (2019)

SYSGENET: a meeting report from a new European network for systems genetics
por: Schughart, Klaus
Publicado: (2010)

Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections
por: Srivastava, Barkha, et al.
Publicado: (2009)

Pathway mapping of leukocyte transcriptome in influenza patients reveals distinct pathogenic mechanisms associated with progression to severe infection
por: Zerbib, Yoann, et al.
Publicado: (2020)

Severe Acute Respiratory Infections With Influenza and Noninfluenza Respiratory Viruses: Yemen, 2011-2016
por: Al Amad, Mohammad Abdullah, et al.
Publicado: (2019)

Severe respiratory failure associated with influenza B virus infection
por: Kato, Shinpei, et al.
Publicado: (2015)

The national and provincial burden of medically attended influenza‐associated influenza‐like illness and severe acute respiratory illness in the Democratic Republic of Congo, 2013‐2015
por: Babakazo, Pélagie, et al.
Publicado: (2018)

Acute hypoxemic respiratory failure in children: case mix and the utility of respiratory severity indices
por: Peters, M. J., et al.
Publicado: (2013)

Newly Recognized Causes of Acute Lung Injury: Transfusion of Blood Products, Severe Acute Respiratory Syndrome, and Avian Influenza
por: Looney, Mark R.
Publicado: (2006)

Severe Childhood Respiratory Viral Infections
por: Hon, Kam-Lun, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_utfrf4e5k1tggp378g12cbuu5d