LITAF Mutations Associated with Charcot-Marie-Tooth Disease 1C Show Mislocalization from the Late Endosome/Lysosome to the Mitochondria

Charcot-Marie-Tooth (CMT) disease is one of the most common heritable neuromuscular disorders, affecting 1 in every 2500 people. Mutations in LITAF have been shown to be causative for CMT type 1C disease. In this paper we explore the subcellular localization of wild type LITAF and mutant forms of LI...

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Detalles Bibliográficos
Autores principales: Ferreira Lacerda, Andressa, Hartjes, Emily, Brunetti, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110028/
https://www.ncbi.nlm.nih.gov/pubmed/25058650
http://dx.doi.org/10.1371/journal.pone.0103454

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