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Lytic Gene Expression Is Frequent in HSV-1 Latent Infection and Correlates with the Engagement of a Cell-Intrinsic Transcriptional Response
Herpes simplex viruses (HSV) are significant human pathogens that provide one of the best-described examples of viral latency and reactivation. HSV latency occurs in sensory neurons, being characterized by the absence of virus replication and only fragmentary evidence of protein production. In mouse...
Autores principales: | Ma, Joel Z., Russell, Tiffany A., Spelman, Tim, Carbone, Francis R., Tscharke, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110040/ https://www.ncbi.nlm.nih.gov/pubmed/25058429 http://dx.doi.org/10.1371/journal.ppat.1004237 |
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