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Lytic Gene Expression Is Frequent in HSV-1 Latent Infection and Correlates with the Engagement of a Cell-Intrinsic Transcriptional Response

Herpes simplex viruses (HSV) are significant human pathogens that provide one of the best-described examples of viral latency and reactivation. HSV latency occurs in sensory neurons, being characterized by the absence of virus replication and only fragmentary evidence of protein production. In mouse...

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Detalles Bibliográficos
Autores principales: Ma, Joel Z., Russell, Tiffany A., Spelman, Tim, Carbone, Francis R., Tscharke, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110040/
https://www.ncbi.nlm.nih.gov/pubmed/25058429
http://dx.doi.org/10.1371/journal.ppat.1004237

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