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Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report
Primary neurolymphomatosis is an extremely rare tumor. We report the case of a 74-year-old patient presenting with dysphagia and hoarseness. Initial contrast-enhanced computed tomography of the head, neck, and chest did not reveal any lesions. His symptoms improved with short-term administration of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110151/ https://www.ncbi.nlm.nih.gov/pubmed/25083392 http://dx.doi.org/10.1055/s-0033-1363505 |
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author | Sakai, Naoto Ito-Yamashita, Tae Takahashi, Goro Baba, Satoshi Koizumi, Shinichiro Yamasaki, Tomohiro Tokuyama, Tsutomu Namba, Hiroki |
author_facet | Sakai, Naoto Ito-Yamashita, Tae Takahashi, Goro Baba, Satoshi Koizumi, Shinichiro Yamasaki, Tomohiro Tokuyama, Tsutomu Namba, Hiroki |
author_sort | Sakai, Naoto |
collection | PubMed |
description | Primary neurolymphomatosis is an extremely rare tumor. We report the case of a 74-year-old patient presenting with dysphagia and hoarseness. Initial contrast-enhanced computed tomography of the head, neck, and chest did not reveal any lesions. His symptoms improved with short-term administration of prednisone but recurred and deteriorated. Magnetic resonance (MR) imaging revealed a tumor along the ninth and tenth cranial nerves across the jugular foramen. Fluorine-18 fluorodeoxyglucose positron emission tomography indicated this was a primary tumor. Repeated MR imaging after 2 months revealed considerable tumor enlargement. A left suboccipital craniotomy was performed to remove the tumor that infiltrated the ninth and tenth cranial nerves. The histopathologic diagnosis was diffuse large B-cell lymphoma. Although focal radiation therapy was administered to ensure complete eradication of the tumor, the patient died of aspiration pneumonia with systemic metastasis. To our knowledge, this is the first reported case of primary neurolymphomatosis in the lower cranial nerves. |
format | Online Article Text |
id | pubmed-4110151 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-41101512014-08-01 Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report Sakai, Naoto Ito-Yamashita, Tae Takahashi, Goro Baba, Satoshi Koizumi, Shinichiro Yamasaki, Tomohiro Tokuyama, Tsutomu Namba, Hiroki J Neurol Surg Rep Article Primary neurolymphomatosis is an extremely rare tumor. We report the case of a 74-year-old patient presenting with dysphagia and hoarseness. Initial contrast-enhanced computed tomography of the head, neck, and chest did not reveal any lesions. His symptoms improved with short-term administration of prednisone but recurred and deteriorated. Magnetic resonance (MR) imaging revealed a tumor along the ninth and tenth cranial nerves across the jugular foramen. Fluorine-18 fluorodeoxyglucose positron emission tomography indicated this was a primary tumor. Repeated MR imaging after 2 months revealed considerable tumor enlargement. A left suboccipital craniotomy was performed to remove the tumor that infiltrated the ninth and tenth cranial nerves. The histopathologic diagnosis was diffuse large B-cell lymphoma. Although focal radiation therapy was administered to ensure complete eradication of the tumor, the patient died of aspiration pneumonia with systemic metastasis. To our knowledge, this is the first reported case of primary neurolymphomatosis in the lower cranial nerves. Georg Thieme Verlag KG 2014-01-16 2014-08 /pmc/articles/PMC4110151/ /pubmed/25083392 http://dx.doi.org/10.1055/s-0033-1363505 Text en © Thieme Medical Publishers |
spellingShingle | Article Sakai, Naoto Ito-Yamashita, Tae Takahashi, Goro Baba, Satoshi Koizumi, Shinichiro Yamasaki, Tomohiro Tokuyama, Tsutomu Namba, Hiroki Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report |
title | Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report |
title_full | Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report |
title_fullStr | Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report |
title_full_unstemmed | Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report |
title_short | Primary Neurolymphomatosis of the Lower Cranial Nerves Presenting as Dysphagia and Hoarseness: A Case Report |
title_sort | primary neurolymphomatosis of the lower cranial nerves presenting as dysphagia and hoarseness: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110151/ https://www.ncbi.nlm.nih.gov/pubmed/25083392 http://dx.doi.org/10.1055/s-0033-1363505 |
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