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Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma

Genetic mutations in tumor cells cause several unique metabolic phenotypes that are critical for cancer cell proliferation. Mutations in the tyrosine kinase epidermal growth factor receptor (EGFR) induce oncogenic addiction in lung adenocarcinoma (LAD). However, the linkage between oncogenic mutated...

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Detalles Bibliográficos
Autores principales:	Makinoshima, Hideki, Takita, Masahiro, Matsumoto, Shingo, Yagishita, Atsushi, Owada, Satoshi, Esumi, Hiroyasu, Tsuchihara, Katsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110289/ https://www.ncbi.nlm.nih.gov/pubmed/24928511 http://dx.doi.org/10.1074/jbc.M114.575464

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