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Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
Retromer is a protein assembly that plays a central role in orchestrating export of transmembrane-spanning cargo proteins from endosomes into retrieval pathways destined for the Golgi apparatus and the plasma membrane [1]. Recently, a specific mutation in the retromer component VPS35, VPS35(D620N),...
Autores principales: | McGough, Ian J., Steinberg, Florian, Jia, Da, Barbuti, Peter A., McMillan, Kirsty J., Heesom, Kate J., Whone, Alan L., Caldwell, Maeve A., Billadeau, Daniel D., Rosen, Michael K., Cullen, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110399/ https://www.ncbi.nlm.nih.gov/pubmed/24980502 http://dx.doi.org/10.1016/j.cub.2014.06.024 |
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