Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation

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Retromer is a protein assembly that plays a central role in orchestrating export of transmembrane-spanning cargo proteins from endosomes into retrieval pathways destined for the Golgi apparatus and the plasma membrane [1]. Recently, a specific mutation in the retromer component VPS35, VPS35(D620N),...

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Detalles Bibliográficos
Autores principales: McGough, Ian J., Steinberg, Florian, Jia, Da, Barbuti, Peter A., McMillan, Kirsty J., Heesom, Kate J., Whone, Alan L., Caldwell, Maeve A., Billadeau, Daniel D., Rosen, Michael K., Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110399/
https://www.ncbi.nlm.nih.gov/pubmed/24980502
http://dx.doi.org/10.1016/j.cub.2014.06.024
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