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Virtual Screening of compounds to 1-deoxy-Dxylulose 5-phosphate reductoisomerase (DXR) from Plasmodium falciparum

The 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) protein (Gen Bank ID AAN37254.1) from Plasmodium falciparum is a potential drug target. Therefore, it is of interest to screen DXR against a virtual library of compounds (at the ZINC database) for potential binders as possible inhibitors. Thi...

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Detalles Bibliográficos
Autores principales:	Chaudhary, Kamal Kumar, Prasad, C.V.S. Siva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2014
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110427/ https://www.ncbi.nlm.nih.gov/pubmed/25097379 http://dx.doi.org/10.6026/97320630010358

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