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Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China
The overall survival of patients with cervical cancer has improved due to detection at an early stage and availability of comprehensive treatments in China. As patients' lives prolonged, it is important to understand their health-related quality of life (QoL) during and after treatment. We used...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sun Yat-sen University Cancer Center
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110466/ https://www.ncbi.nlm.nih.gov/pubmed/24698497 http://dx.doi.org/10.5732/cjc.013.10139 |
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author | Zhao, Zhi-Mei Pan, Xiong-Fei Lv, Si-Han Xie, Yao Zhang, Shao-Kai Qiao, You-Lin Qi, Xiao-Rong Yang, Chun-Xia Zhao, Fang-Hui |
author_facet | Zhao, Zhi-Mei Pan, Xiong-Fei Lv, Si-Han Xie, Yao Zhang, Shao-Kai Qiao, You-Lin Qi, Xiao-Rong Yang, Chun-Xia Zhao, Fang-Hui |
author_sort | Zhao, Zhi-Mei |
collection | PubMed |
description | The overall survival of patients with cervical cancer has improved due to detection at an early stage and availability of comprehensive treatments in China. As patients' lives prolonged, it is important to understand their health-related quality of life (QoL) during and after treatment. We used the EQ-5D questionnaire to assess QoL of 194 patients with cervical lesions at Sichuan University West China Second Hospital between May 2010 and January 2011. Patients were surveyed before primary treatment and at 1, 3, and 6 months after primary treatment. Results showed a consistent decline in EQ-5D scores in the spectrum of cervical lesions at each time point after treatment (all P < 0.05). For patients with precursor lesions, there was an increasing trend along the timeline of treatment (P < 0.01). For patients with early-stage cervical cancer, EQ-5D scores declined in the first month (P = 0.01) and gradually increased to higher levels at 6 months post-treatment than those before treatment (P < 0.01). EQ-5D scores followed a similar trend in patients with advanced cervical cancer (P = 0.04), though they did not statistically rebound after 6 months (0.84 ± 0.19 vs. 0.86 ± 0.11, P = 0.62). Regarding advanced cervical cancer, EQ-5D scores for women above 40 years of age appeared to recover more rapidly and reached higher levels than those for women below 40 years (P = 0.03). Caution and extra care are recommended in the early period of cervical cancer treatment given the slight deterioration in the QoL, and in particular, for younger cervical cancer patients. Our study implies that health care providers may need to improve the health-related QoL of cervical cancer patients. |
format | Online Article Text |
id | pubmed-4110466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Sun Yat-sen University Cancer Center |
record_format | MEDLINE/PubMed |
spelling | pubmed-41104662014-07-25 Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China Zhao, Zhi-Mei Pan, Xiong-Fei Lv, Si-Han Xie, Yao Zhang, Shao-Kai Qiao, You-Lin Qi, Xiao-Rong Yang, Chun-Xia Zhao, Fang-Hui Chin J Cancer Original Article The overall survival of patients with cervical cancer has improved due to detection at an early stage and availability of comprehensive treatments in China. As patients' lives prolonged, it is important to understand their health-related quality of life (QoL) during and after treatment. We used the EQ-5D questionnaire to assess QoL of 194 patients with cervical lesions at Sichuan University West China Second Hospital between May 2010 and January 2011. Patients were surveyed before primary treatment and at 1, 3, and 6 months after primary treatment. Results showed a consistent decline in EQ-5D scores in the spectrum of cervical lesions at each time point after treatment (all P < 0.05). For patients with precursor lesions, there was an increasing trend along the timeline of treatment (P < 0.01). For patients with early-stage cervical cancer, EQ-5D scores declined in the first month (P = 0.01) and gradually increased to higher levels at 6 months post-treatment than those before treatment (P < 0.01). EQ-5D scores followed a similar trend in patients with advanced cervical cancer (P = 0.04), though they did not statistically rebound after 6 months (0.84 ± 0.19 vs. 0.86 ± 0.11, P = 0.62). Regarding advanced cervical cancer, EQ-5D scores for women above 40 years of age appeared to recover more rapidly and reached higher levels than those for women below 40 years (P = 0.03). Caution and extra care are recommended in the early period of cervical cancer treatment given the slight deterioration in the QoL, and in particular, for younger cervical cancer patients. Our study implies that health care providers may need to improve the health-related QoL of cervical cancer patients. Sun Yat-sen University Cancer Center 2014-07 /pmc/articles/PMC4110466/ /pubmed/24698497 http://dx.doi.org/10.5732/cjc.013.10139 Text en Chinese Journal of Cancer http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission. |
spellingShingle | Original Article Zhao, Zhi-Mei Pan, Xiong-Fei Lv, Si-Han Xie, Yao Zhang, Shao-Kai Qiao, You-Lin Qi, Xiao-Rong Yang, Chun-Xia Zhao, Fang-Hui Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China |
title | Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China |
title_full | Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China |
title_fullStr | Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China |
title_full_unstemmed | Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China |
title_short | Quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in China |
title_sort | quality of life in women with cervical precursor lesions and cancer: a prospective, 6-month, hospital-based study in china |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110466/ https://www.ncbi.nlm.nih.gov/pubmed/24698497 http://dx.doi.org/10.5732/cjc.013.10139 |
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