Cargando…

Effects of Obesity on Transcriptomic Changes and Cancer Hallmarks in Estrogen Receptor–Positive Breast Cancer

BACKGROUND: Obesity increases the risk of cancer death among postmenopausal women with estrogen receptor–positive (ER+) breast cancer, but the direct evidence for the mechanisms is lacking. The purpose of this study is to demonstrate direct evidence for the mechanisms mediating this epidemiologic ph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fuentes-Mattei, Enrique, Velazquez-Torres, Guermarie, Phan, Liem, Zhang, Fanmao, Chou, Ping-Chieh, Shin, Ji-Hyun, Choi, Hyun Ho, Chen, Jiun-Sheng, Zhao, Ruiying, Chen, Jian, Gully, Chris, Carlock, Colin, Qi, Yuan, Zhang, Ya, Wu, Yun, Esteva, Francisco J., Luo, Yongde, McKeehan, Wallace L., Ensor, Joe, Hortobagyi, Gabriel N., Pusztai, Lajos, Fraser Symmans, W., Lee, Mong-Hong, Jim Yeung, Sai-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110474/ https://www.ncbi.nlm.nih.gov/pubmed/24957076 http://dx.doi.org/10.1093/jnci/dju158

Ejemplares similares

Impact of diabetes on promoting the growth of breast cancer
por: Chou, Ping‐Chieh, et al.
Publicado: (2021)

Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer
por: Gully, Christopher P, et al.
Publicado: (2010)

Exenatide improves glucocorticoid-induced glucose intolerance in mice
por: Zhao, Ruiying, et al.
Publicado: (2011)

Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage
por: Su, Chun-Hui, et al.
Publicado: (2010)

Diabetes mellitus type 2 drives metabolic reprogramming to promote pancreatic cancer growth
por: Velazquez-Torres, Guermarie, et al.
Publicado: (2020)

Stressed Liver and Muscle Call on Adipocytes with FGF21
por: Luo, Yongde, et al.
Publicado: (2013)

Roles of endocrine FGF signaling in metabolic health and cancer
por: Luo, Yongde, et al.
Publicado: (2014)

The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth
por: Feng, Yin-Hsun, et al.
Publicado: (2011)

CSN6 drives carcinogenesis by positively regulating Myc stability
por: Chen, Jian, et al.
Publicado: (2014)

Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations
por: Luo, Yongde, et al.
Publicado: (2013)

CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer
por: Esteva, Francisco J, et al.
Publicado: (2007)

Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB
por: Yang, Chaofeng, et al.
Publicado: (2012)

Palm OS programming: the developer's guide
por: Rhodes, Neil, et al.
Publicado: (2002)

Palm programming: the developer's guide
por: Rhodes, Neil, et al.
Publicado: (1999)

Evaluation of biological pathways involved in chemotherapy response in breast cancer
por: Tordai, Attila, et al.
Publicado: (2008)

The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming
por: Phan, Liem, et al.
Publicado: (2015)

Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress
por: Yang, Chaofeng, et al.
Publicado: (2012)

Translating the biology of aging into novel therapeutics for Alzheimer disease
por: Hara, Yuko, et al.
Publicado: (2019)

COP1 enhances ubiquitin-mediated degradation of p27(Kip1) to promote cancer cell growth
por: Choi, Hyun Ho, et al.
Publicado: (2015)

The Bimodality Index: A Criterion for Discovering and Ranking Bimodal Signatures from Cancer Gene Expression Profiling Data
por: Wang, Jing, et al.
Publicado: (2009)

Bone metastasis-related signaling pathways in breast cancers stratified by estrogen receptor status
por: Hayashi, Naoki, et al.
Publicado: (2017)

Dual Function Microtubule- and Mitochondria-Associated Proteins Mediate Mitotic Cell Death
por: Liu, Leyuan, et al.
Publicado: (2009)

Acetylated microtubules are required for fusion of autophagosomes with lysosomes
por: Xie, Rui, et al.
Publicado: (2010)

Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems
por: Hess, Kenneth R, et al.
Publicado: (2011)

Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer
por: McGovern, Susan L, et al.
Publicado: (2012)

Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies
por: Phan, Liem Minh, et al.
Publicado: (2014)

Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress
por: Yang, Chaofeng, et al.
Publicado: (2013)

Fingerprinting Lymph Node Metastases
por: Symmans, W. Fraser, et al.
Publicado: (2008)

Novel Functional Assay for Spindle-Assembly Checkpoint by Cyclin-Dependent Kinase Activity to Predict Taxane Chemosensitivity in Breast Tumor Patient
por: Torikoshi, Yasuhiro, et al.
Publicado: (2013)

PIK3CA-activating mutations and chemotherapy sensitivity in stage II–III breast cancer
por: Liedtke, Cornelia, et al.
Publicado: (2008)

Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments
por: Qi, Yuan, et al.
Publicado: (2015)

Polymicrobial Nature of Chronic Diabetic Foot Ulcer Biofilm Infections Determined Using Bacterial Tag Encoded FLX Amplicon Pyrosequencing (bTEFAP)
por: Dowd, Scot E., et al.
Publicado: (2008)

Hallmarks of cancer and hallmarks of aging
por: Blagosklonny, Mikhail V.
Publicado: (2022)

Maximum predictive power of the microarray-based models for clinical outcomes is limited by correlation between endpoint and gene expression profile
por: Zhao, Chen, et al.
Publicado: (2011)

FRS2α is Essential for the Fibroblast Growth Factor to Regulate the mTOR Pathway and Autophagy in Mouse Embryonic Fibroblasts
por: Lin, Xiang, et al.
Publicado: (2011)

Gene expression profiling of breast cancer
por: Pusztai, Lajos
Publicado: (2009)

Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy
por: Lu, Weiqin, et al.
Publicado: (2012)

Correction: Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy
por: Lu, Weiqin, et al.
Publicado: (2017)

COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer
por: Gao, Shujun, et al.
Publicado: (2015)

Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression
por: Huang, Yanqing, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ltfg1ekschg7vddg3sjkc41eb7