Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2)

BACKGROUND: The purpose of the present study was to continue the investigation of the membrane transport mechanisms of 20-(S)-camptothecin (CPT) in order to understand the possible role of membrane transporters on its oral bioavailability and disposition. METHODS: The intestinal transport kinetics o...

Descripción completa

Detalles Bibliográficos
Autores principales: Lalloo, Anita K, Luo, Feng R, Guo, Ailan, Paranjpe, Pankaj V, Lee, Sung-Hack, Vyas, Viral, Rubin, Eric, Sinko, Patrick J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC411064/
https://www.ncbi.nlm.nih.gov/pubmed/15125776
http://dx.doi.org/10.1186/1741-7015-2-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC411064/
https://www.ncbi.nlm.nih.gov/pubmed/15125776
http://dx.doi.org/10.1186/1741-7015-2-16

Ejemplares similares