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A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival

BACKGROUND: BRCA1 mutation carriers have an 85% risk of developing breast cancer but the risk of developing non-hereditary breast cancer is difficult to assess. Our objective is to test whether a DNA methylation (DNAme) signature derived from BRCA1 mutation carriers is able to predict non-hereditary...

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Detalles Bibliográficos
Autores principales:	Anjum, Shahzia, Fourkala, Evangelia-Ourania, Zikan, Michal, Wong, Andrew, Gentry-Maharaj, Aleksandra, Jones, Allison, Hardy, Rebecca, Cibula, David, Kuh, Diana, Jacobs, Ian J, Teschendorff, Andrew E, Menon, Usha, Widschwendter, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110671/ https://www.ncbi.nlm.nih.gov/pubmed/25067956 http://dx.doi.org/10.1186/gm567

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