Cargando…

Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signaling

Local environmental cues are indispensable for axonal growth and guidance during brain circuit formation. Here, we combine genetic and pharmacological tools, as well as systems neuroanatomy in human fetuses and mouse models, to study the role of endocannabinoid and Slit/Robo signaling in axonal grow...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alpár, Alán, Tortoriello, Giuseppe, Calvigioni, Daniela, Niphakis, Micah J, Milenkovic, Ivan, Bakker, Joanne, Cameron, Gary A, Hanics, János, Morris, Claudia V, Fuzik, János, Kovacs, Gabor G, Cravatt, Benjamin F, Parnavelas, John G, Andrews, William D, Hurd, Yasmin L, Keimpema, Erik, Harkany, Tibor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110686/ https://www.ncbi.nlm.nih.gov/pubmed/25030704 http://dx.doi.org/10.1038/ncomms5421

Ejemplares similares

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling
por: Keimpema, Erik, et al.
Publicado: (2013)

Robo2 is required for Slit-mediated intraretinal axon guidance
por: Thompson, Hannah, et al.
Publicado: (2009)

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons
por: Cariboni, Anna, et al.
Publicado: (2012)

Neuropathology of the Brainstem to Mechanistically Understand and to Treat Alzheimer’s Disease
por: Patthy, Ágoston, et al.
Publicado: (2021)

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves
por: Mommersteeg, Mathilda T.M., et al.
Publicado: (2015)

Integration of electrophysiological recordings with single-cell RNA-seq data identifies novel neuronal subtypes
por: Fuzik, János, et al.
Publicado: (2015)

The p(l)ot thickens: cannabinoid receptors on astroglial mitochondria coordinate animal behaviors by regulating lactate availability for neurons
por: Keimpema, Erik, et al.
Publicado: (2020)

Slit–Robo signalling in heart development
por: Zhao, Juanjuan, et al.
Publicado: (2018)

The Role of the Slit/Robo Signaling Pathway
por: Tong, Mingfu, et al.
Publicado: (2019)

Protracted brain development in a rodent model of extreme longevity
por: Penz, Orsolya K., et al.
Publicado: (2015)

The SLIT/ROBO Pathway in Liver Fibrosis and Cancer
por: Basha, Sreenivasulu, et al.
Publicado: (2023)

Slit/Robo signaling regulates Leydig cell steroidogenesis
por: Martinot, Emmanuelle, et al.
Publicado: (2021)

Role of Slit/Robo Signaling pathway in Bone Metabolism
por: Jiang, Lingyu, et al.
Publicado: (2022)

Effect of Slit/Robo signaling on regeneration in lung emphysema
por: Park, Jin-Soo, et al.
Publicado: (2021)

Multiple amygdaloid divisions of arcopallium send convergent projections to the nucleus accumbens and neighboring subpallial amygdala regions in the domestic chicken: a selective pathway tracing and reconstruction study
por: Hanics, János, et al.
Publicado: (2016)

Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
por: Evans, Timothy A, et al.
Publicado: (2015)

Coevolution of Axon Guidance Molecule Slit and Its Receptor Robo
por: Yu, Qi, et al.
Publicado: (2014)

Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling
por: Morin-Poulard, Ismaël, et al.
Publicado: (2016)

Contralateral migration of oculomotor neurons is regulated by Slit/Robo signaling
por: Bjorke, Brielle, et al.
Publicado: (2016)

Slit-independent guidance of longitudinal axons by Drosophila Robo3
por: Carranza, Abigail, et al.
Publicado: (2023)

Correction: Coevolution of Axon Guidance Molecule Slit and Its Receptor Robo
Publicado: (2014)

Slit-miR-218-Robo axis regulates retinal neovascularization
por: Kong, Yichun, et al.
Publicado: (2016)

The Expression of the SLIT–ROBO Family in Adult Patients with Acute Myeloid Leukemia
por: Gołos, Aleksandra, et al.
Publicado: (2019)

Research Progress on Slit/Robo Pathway in Pancreatic Cancer: Emerging and Promising
por: Ding, Cheng, et al.
Publicado: (2020)

Beyond Axon Guidance: Roles of Slit-Robo Signaling in Neocortical Formation
por: Gonda, Yuko, et al.
Publicado: (2020)

Slit-Robo expression in the leech nervous system: insights into eyespot evolution
por: Kwak, Hee-Jin, et al.
Publicado: (2023)

Insulin-like growth factor I and its binding protein-3 are regulators of lactation and maternal responsiveness
por: Lékó, András H., et al.
Publicado: (2017)

The emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancers
por: Huang, Tingting, et al.
Publicado: (2015)

Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization
por: Campbell, Douglas S., et al.
Publicado: (2013)

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma
por: Marko, Tracy A., et al.
Publicado: (2016)

Screen for Slit/Robo signaling in trunk neural cells reveals new players
por: Martinez, Darwin, et al.
Publicado: (2018)

Targeting the SLIT/ROBO pathway in tumor progression: molecular mechanisms and therapeutic perspectives
por: Jiang, Zhengdong, et al.
Publicado: (2019)

The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis
por: Sehring, Ivonne M, et al.
Publicado: (2022)

Role of the SLIT-ROBO signaling pathway in renal pathophysiology and various renal diseases
por: Feng, Li, et al.
Publicado: (2023)

Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis
por: Xiao, Wenyuan, et al.
Publicado: (2022)

Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer’s disease
por: Zahola, Péter, et al.
Publicado: (2019)

Mapping the Protein Interaction Landscape for Fully Functionalized Small-Molecule Probes in Human Cells
por: Kambe, Tohru, et al.
Publicado: (2014)

The role of SLIT-ROBO signaling in proliferative diabetic retinopathy and retinal pigment epithelial cells
por: Zhou, Weiyan, et al.
Publicado: (2011)

Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis
por: Denk, Alexandra E, et al.
Publicado: (2010)

USP33, a new player in lung cancer, mediates Slit-Robo signaling
por: Wen, Pushuai, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ceskki7d9fiildeio0lsk02l0q