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Effects of error-correction of heterozygous next-generation sequencing data

BACKGROUND: Error correction is an important step in increasing the quality of next-generation sequencing data for downstream analysis and use. Polymorphic datasets are a challenge for many bioinformatic software packages that are designed for or assume homozygosity of an input dataset. This assumpt...

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Detalles Bibliográficos
Autores principales: Fujimoto, M Stanley, Bodily, Paul M, Okuda, Nozomu, Clement, Mark J, Snell, Quinn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110727/
https://www.ncbi.nlm.nih.gov/pubmed/25077414
http://dx.doi.org/10.1186/1471-2105-15-S7-S3