Cytokine-Regulated GADD45G Induces Differentiation and Lineage Selection in Hematopoietic Stem Cells

The balance of self-renewal and differentiation in long-term repopulating hematopoietic stem cells (LT-HSC) must be strictly controlled to maintain blood homeostasis and to prevent leukemogenesis. Hematopoietic cytokines can induce differentiation in LT-HSCs; however, the molecular mechanism orchest...

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Detalles Bibliográficos
Autores principales: Thalheimer, Frederic B., Wingert, Susanne, De Giacomo, Pangrazio, Haetscher, Nadine, Rehage, Maike, Brill, Boris, Theis, Fabian J., Hennighausen, Lothar, Schroeder, Timm, Rieger, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110750/
https://www.ncbi.nlm.nih.gov/pubmed/25068120
http://dx.doi.org/10.1016/j.stemcr.2014.05.010

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