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Comparable Generation of Activin-Induced Definitive Endoderm via Additive Wnt or BMP Signaling in Absence of Serum

There is considerable interest in differentiating human pluripotent stem cells (hPSCs) into definitive endoderm (DE) and pancreatic cells for in vitro disease modeling and cell replacement therapy. Numerous protocols use fetal bovine serum, which contains poorly defined factors to induce DE formatio...

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Detalles Bibliográficos
Autores principales:	Teo, Adrian Kee Keong, Valdez, Ivan Achel, Dirice, Ercument, Kulkarni, Rohit N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110751/ https://www.ncbi.nlm.nih.gov/pubmed/25068117 http://dx.doi.org/10.1016/j.stemcr.2014.05.007

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