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Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis
Current therapies for multiple sclerosis (MS) are largely palliative, not curative. Mesenchymal stem cells (MSCs) harbor regenerative and immunosuppressive functions, indicating a potential therapy for MS, yet the variability and low potency of MSCs from adult sources hinder their therapeutic potent...
Autores principales: | Wang, Xiaofang, Kimbrel, Erin A., Ijichi, Kumiko, Paul, Debayon, Lazorchak, Adam S., Chu, Jianlin, Kouris, Nicholas A., Yavanian, Gregory J., Lu, Shi-Jiang, Pachter, Joel S., Crocker, Stephen J., Lanza, Robert, Xu, Ren-He |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110787/ https://www.ncbi.nlm.nih.gov/pubmed/25068126 http://dx.doi.org/10.1016/j.stemcr.2014.04.020 |
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