Cargando…
Modulating Innate Immunity Improves Hepatitis C Virus Infection and Replication in Stem Cell-Derived Hepatocytes
In this study, human embryonic stem cell-derived hepatocytes (hESC-Heps) were investigated for their ability to support hepatitis C virus (HCV) infection and replication. hESC-Heps were capable of supporting the full viral life cycle, including the release of infectious virions. Although supportive,...
Autores principales: | Zhou, Xiaoling, Sun, Pingnan, Lucendo-Villarin, Baltasar, Angus, Allan G.N., Szkolnicka, Dagmara, Cameron, Kate, Farnworth, Sarah L., Patel, Arvind H., Hay, David C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110790/ https://www.ncbi.nlm.nih.gov/pubmed/25068132 http://dx.doi.org/10.1016/j.stemcr.2014.04.018 |
Ejemplares similares
-
Modeling Human Liver Biology Using Stem Cell-Derived Hepatocytes
por: Sun, Pingnan, et al.
Publicado: (2013) -
Human PSC-Derived Hepatocytes Express Low Levels of Viral Pathogen Recognition Receptors, but Are Capable of Mounting an Effective Innate Immune Response
por: Fischer, Lena, et al.
Publicado: (2020) -
Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes
por: Cameron, Kate, et al.
Publicado: (2015) -
Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes
por: Sinton, Matthew C., et al.
Publicado: (2021) -
Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells
por: Lyall, Marcus J., et al.
Publicado: (2018)