Association of cancer metabolism-related proteins with oral carcinogenesis – indications for chemoprevention and metabolic sensitizing of oral squamous cell carcinoma?

BACKGROUND: Tumor metabolism is a crucial factor for the carcinogenesis of oral squamous cell carcinoma (OSCC). METHODS: Expression of IGF-R1, glycolysis-related proteins (GLUT-1, HK 2, PFK-1, LDHA, TKTL1), mitochondrial enzymes (SDHA, SDHB, ATP synthase) were analyzed in normal oral mucosa (n = 5),...

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Detalles Bibliográficos
Autores principales: Grimm, Martin, Cetindis, Marcel, Lehmann, Max, Biegner, Thorsten, Munz, Adelheid, Teriete, Peter, Kraut, Wiebke, Reinert, Siegmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110933/
https://www.ncbi.nlm.nih.gov/pubmed/25048361
http://dx.doi.org/10.1186/1479-5876-12-208

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