Down-Regulation of Complement Receptors on the Surface of Host Monocyte Even as In Vitro Complement Pathway Blocking Interferes in Dengue Infection

In dengue virus (DENV) infection, complement system (CS) activation appears to have protective and pathogenic effects. In severe dengue fever (DF), the levels of DENV non-structural-1 protein and of the products of complement activation, including C3a, C5a and SC5b-9, are higher before vascular leak...

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Detalles Bibliográficos
Autores principales: Marinho, Cintia Ferreira, Azeredo, Elzinandes Leal, Torrentes-Carvalho, Amanda, Marins-Dos-Santos, Alessandro, Kubelka, Claire Fernandes, de Souza, Luiz José, Cunha, Rivaldo Venâncio, de-Oliveira-Pinto, Luzia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111305/
https://www.ncbi.nlm.nih.gov/pubmed/25061945
http://dx.doi.org/10.1371/journal.pone.0102014

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