Cloning and Characterization of a Norbelladine 4′-O-Methyltransferase Involved in the Biosynthesis of the Alzheimer’s Drug Galanthamine in Narcissus sp. aff. pseudonarcissus

Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer’s disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum). Despite its importance as a medicine, no genes involved in the biosyn...

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Detalles Bibliográficos
Autores principales: Kilgore, Matthew B., Augustin, Megan M., Starks, Courtney M., O’Neil-Johnson, Mark, May, Gregory D., Crow, John A., Kutchan, Toni M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111509/
https://www.ncbi.nlm.nih.gov/pubmed/25061748
http://dx.doi.org/10.1371/journal.pone.0103223

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