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Intoxication of Host Cells by the T3SS Phospholipase ExoU: PI(4,5)P(2)-Associated, Cytoskeletal Collapse and Late Phase Membrane Blebbing
Pseudomonas aeruginosa is an opportunistic pathogen that is associated with hospital-acquired infections, ventilator-associated pneumonia, and morbidity of immunocompromised individuals. A subpopulation of P. aeruginosa encodes a protein, ExoU, which exhibits acute cytotoxicity. Toxicity is directly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111512/ https://www.ncbi.nlm.nih.gov/pubmed/25061861 http://dx.doi.org/10.1371/journal.pone.0103127 |