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Intoxication of Host Cells by the T3SS Phospholipase ExoU: PI(4,5)P(2)-Associated, Cytoskeletal Collapse and Late Phase Membrane Blebbing

Pseudomonas aeruginosa is an opportunistic pathogen that is associated with hospital-acquired infections, ventilator-associated pneumonia, and morbidity of immunocompromised individuals. A subpopulation of P. aeruginosa encodes a protein, ExoU, which exhibits acute cytotoxicity. Toxicity is directly...

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Detalles Bibliográficos
Autores principales:	Sato, Hiromi, Frank, Dara W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111512/ https://www.ncbi.nlm.nih.gov/pubmed/25061861 http://dx.doi.org/10.1371/journal.pone.0103127

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