The mGluR5 Antagonist Fenobam Induces Analgesic Conditioned Place Preference in Mice with Spared Nerve Injury

Antagonists of metabotropic glutamate receptors (mGluRs) have the potential to act as analgesic drugs that may help alleviate chronic pain. This study was done to look at the possible rewarding properties of the mGluR5 antagonist, fenobam, in a cognitive assay. Analgesic conditioned place preference...

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Detalles Bibliográficos
Autores principales: Lax, Neil C., George, David C., Ignatz, Christopher, Kolber, Benedict J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111598/
https://www.ncbi.nlm.nih.gov/pubmed/25061818
http://dx.doi.org/10.1371/journal.pone.0103524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111598/
https://www.ncbi.nlm.nih.gov/pubmed/25061818
http://dx.doi.org/10.1371/journal.pone.0103524

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