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Induction monotherapy with sirolimus has selected beneficial effects on glomerular and tubulointersititial injury in nephrotoxic serum nephritis

BACKGROUND: The study aimed to test the hypothesis that therapeutic treatment with a mammalian target of rapamycin complex 1 inhibitor reduces renal cell proliferation and attenuates glomerular and tubulointerstitial injury in the early phase of nephrotoxic serum nephritis (NSN) in rats. METHODS: Ma...

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Detalles Bibliográficos
Autores principales:	Succar, Lena, Lai-Kwon, Julia, Nikolic-Paterson, David J, Rangan, Gopala K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111659/ https://www.ncbi.nlm.nih.gov/pubmed/25071375 http://dx.doi.org/10.2147/IJNRD.S64202

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