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Enhanced oral absorption and therapeutic effect of acetylpuerarin based on D-α-tocopheryl polyethylene glycol 1000 succinate nanoemulsions
BACKGROUND: Acetylpuerarin (AP), because of its lower water solubility, shows poor absorption that hinders its therapeutic application. Thus, the aim of this study was to prepare nanoemulsions for AP, enhance its oral bioavailability, and thus improve the therapeutic effect. METHODS: The nanoemulsio...
Autores principales: | Sun, Deqing, Wei, Xinbing, Xue, Xia, Fang, Zengjun, Ren, Manru, Lou, Haiyan, Zhang, Xiumei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111663/ https://www.ncbi.nlm.nih.gov/pubmed/25071371 http://dx.doi.org/10.2147/IJN.S63777 |
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