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Conformational readout of RNA by small ligands

RNA molecules have highly versatile structures that can fold into myriad conformations, providing many potential pockets for binding small molecules. The increasing number of available RNA structures, in complex with proteins, small ligands and in free form, enables the design of new therapeutically...

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Detalles Bibliográficos
Autores principales: Kligun, Efrat, Mandel-Gutfreund, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111737/
https://www.ncbi.nlm.nih.gov/pubmed/23618839
http://dx.doi.org/10.4161/rna.24682