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Conformational readout of RNA by small ligands
RNA molecules have highly versatile structures that can fold into myriad conformations, providing many potential pockets for binding small molecules. The increasing number of available RNA structures, in complex with proteins, small ligands and in free form, enables the design of new therapeutically...
Autores principales: | Kligun, Efrat, Mandel-Gutfreund, Yael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111737/ https://www.ncbi.nlm.nih.gov/pubmed/23618839 http://dx.doi.org/10.4161/rna.24682 |
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