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Impact of CYP2D6 polymorphisms on clinical efficacy & tolerability of metoprolol tartrate

Metoprolol is a selective β-1 adrenergic receptor blocker that undergoes extensive metabolism by the polymorphic enzyme, CYP2D6. Our objective was to investigate the influence of CYP2D6 polymorphisms on efficacy and tolerability of metoprolol tartrate. 281 study participants with uncomplicated hyper...

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Detalles Bibliográficos
Autores principales:	Hamadeh, Issam S., Langaee, Taimour Y., Dwivedi, Ruti, Garcia, Sofia, Burkley, Ben M., Chapman, Arlene B., Gums, John G., Turner, Stephen T., Gong, Yan, Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111800/ https://www.ncbi.nlm.nih.gov/pubmed/24637943 http://dx.doi.org/10.1038/clpt.2014.62

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