Twice-Daily Subcutaneous Injection of Kisspeptin-54 Does Not Abolish Menstrual Cyclicity in Healthy Female Volunteers

BACKGROUND: Kisspeptin is a critical hypothalamic regulator of reproductive function. Chronic kisspeptin administration causes profound tachyphylaxis in male monkeys and in women with functional hypothalamic amenorrhea. The pharmacological effects of chronic kisspeptin exposure in healthy women with...

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Detalles Bibliográficos
Autores principales: Jayasena, C. N., Comninos, A. N., Nijher, G. M. K., Abbara, A., De Silva, A., Veldhuis, J. D., Ratnasabapathy, R., Izzi-Engbeaya, C., Lim, A., Patel, D. A., Ghatei, M. A., Bloom, S. R., Dhillo, W. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2013
Materias:
Endocrine Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111853/
https://www.ncbi.nlm.nih.gov/pubmed/24030945
http://dx.doi.org/10.1210/jc.2013-1069

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