Identification of In Vitro Metabolites of Amoxicillin in Human Liver Microsomes by LC–ESI/MS

Amoxicillin (AMOX) metabolism in human liver microsomes was studied in vitro using liquid chromatography–mass spectrometry (LC/MS). Amoxicillin was incubated with human liver microsomes along with NADPH, and the reaction mixture was analyzed by LC/MS to obtain the specific metabolic profile of the s...

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Detalles Bibliográficos
Autores principales: Szultka, Malgorzata, Krzeminski, Rafal, Jackowski, Marek, Buszewski, Boguslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111861/
https://www.ncbi.nlm.nih.gov/pubmed/25089048
http://dx.doi.org/10.1007/s10337-014-2648-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111861/
https://www.ncbi.nlm.nih.gov/pubmed/25089048
http://dx.doi.org/10.1007/s10337-014-2648-2

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