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Identification of In Vitro Metabolites of Amoxicillin in Human Liver Microsomes by LC–ESI/MS
Amoxicillin (AMOX) metabolism in human liver microsomes was studied in vitro using liquid chromatography–mass spectrometry (LC/MS). Amoxicillin was incubated with human liver microsomes along with NADPH, and the reaction mixture was analyzed by LC/MS to obtain the specific metabolic profile of the s...
Autores principales: | Szultka, Malgorzata, Krzeminski, Rafal, Jackowski, Marek, Buszewski, Boguslaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111861/ https://www.ncbi.nlm.nih.gov/pubmed/25089048 http://dx.doi.org/10.1007/s10337-014-2648-2 |
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