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Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA
Escherichia coli RecA is the defining member of a ubiquitous class of DNA strand exchange proteins that are essential for homologous recombination, a pathway that maintains genomic integrity by repairing broken DNA(1). To function, filaments of RecA must nucleate and grow on single-stranded DNA (ssD...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112059/ https://www.ncbi.nlm.nih.gov/pubmed/23103864 http://dx.doi.org/10.1038/nature11598 |