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Bayesian approach to single-cell differential expression analysis

Single-cell data provides means to dissect the composition of complex tissues and specialized cellular environments. However, the analysis of such measurements is complicated by high levels of technical noise and intrinsic biological variability. We describe a probabilistic model of expression magni...

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Detalles Bibliográficos
Autores principales: Kharchenko, Peter V., Silberstein, Lev, Scadden, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112276/
https://www.ncbi.nlm.nih.gov/pubmed/24836921
http://dx.doi.org/10.1038/nmeth.2967