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Families or Unrelated: The Evolving Debate in Genetic Association Studies

To help uncover the genetic determinants of complex disease, a scientist often designs an association study using either unrelated subjects or family members within pedigrees. But which of these two subject recruitment paradigms is preferable? This editorial addresses the debate over the relative me...

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Detalles Bibliográficos
Autores principales: Fardo, David W., Charnigo, Richard, Epstein, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112473/
https://www.ncbi.nlm.nih.gov/pubmed/25077036