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DDX39B (BAT1), TNF and IL6 gene polymorphisms and association with clinical outcomes of patients with Plasmodium vivax malaria
BACKGROUND: DDX39B (BAT1) encodes an RNA helicase known to regulate expression of TNF and IL-6. Elevated levels of these two cytokines are associated with increased severity of clinical malaria. The aim of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs)...
Autores principales: | Mendonça, Vitor RR, Souza, Ligia CL, Garcia, Gabriela C, Magalhães, Belisa ML, Lacerda, Marcus VG, Andrade, Bruno B, Gonçalves, Marilda S, Barral-Netto, Manoel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112608/ https://www.ncbi.nlm.nih.gov/pubmed/25038626 http://dx.doi.org/10.1186/1475-2875-13-278 |
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